Diagnosis and treatment of essential thrombocythemia
نویسندگان
چکیده
منابع مشابه
Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia.
Recent insights into the molecular mechanisms of polycythemia vera (PV) and essential thrombocythemia (ET) are challenging the traditional diagnostic classification of these myeloproliferative disorders (MPDs). Clonality analysis using X-chromosome inactivation patterns has revealed apparent heterogeneity among the MPDs. The recently discovered single somatic activating point mutation in the JA...
متن کاملComments on ELN Recommendations to Diagnosis, Prognosis and Treatment of Polycythemia Vera and Essential Thrombocythemia
Introduction The new genetic and clinical notions on classic myeloproliferative neoplasms (MPN) polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) have modified our criteria for diagnosis, prognosis and therapy but it is as still unclear whether these concepts can be translated into changes of the management of individual patient with MPN. For this reason, an...
متن کاملGuidelines for the diagnosis and treatment of patients with polycythemia vera, essential thrombocythemia and primary myelofibrosis
The Nordic study group on myeloproliferative disorders (NMPD) is a pan-Nordic organisation that has conducted Nordic clinical trials since 2001. NMPD decided in 2006 to write new guidelines, based on already existing national guidelines from the Nordic countries, Italy (1) and Great Britain (2). The first version was published in 2007. The aim has been to write a document that can be used in al...
متن کاملEssential thrombocythemia
Essential thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by a sustained elevation of platelet number with a tendency for thrombosis and hemorrhage. The prevalence in the general population is approximately 30/100,000. The median age at diagnosis is 65 to 70 years, but the disease may occur at any age. The female to male ratio is about 2:1. The clinical pictu...
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ژورنال
عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis
سال: 2008
ISSN: 1880-8808,0915-7441
DOI: 10.2491/jjsth.19.206